Published October 25, 2012
Steve Gallo, CCR's lead software engineer and database administrator, was honored by UB at this year's Inventors and Entrepreneurs Reception.
Steve helped to develop a computer program to enable the rational design of small molecules targeting ribonucleic acid (RNA). RNA is an important potential target for the design of small molecule therapeutics or probes of function. The lack of information about RNA-ligand interactions and the fact that there is no centralized repository of known interactions is significantly hampering developments in the fields of RNA therapeutics and RNA chemical biology. Researchers at UB have developed computational methods to identify druggable RNA targets in genomic sequences and to rationally design small molecule ligands to target them and have licensed their technology to SMaRT Therapeutics. Check out the UB Reporter article for more info.